There are three essential pieces to the gut health puzzle: prebiotics, probiotics, and postbiotics.

If you aren’t very familiar with the “missing third piece,” postbiotics – and why supplementing with them really is as mission-critical as it gets today – you are not alone.

And you’re about to gain a clear and concise understanding of postbiotics, including what to look for and what you’ll want to AVOID, below.

First, though, it’s important for you to know the full picture on…


If you want to live long and live well, your Priority #1 must be focusing on your gut health.

Because, in brief, modern-day research shows that virtually EVERY aspect ofyour health and longevity – from a sharp brain and robust immune system to a healthy heart, liver, lungs, muscles, and skin – is at least in part dependent on it!

Now, especially if you occasionally suffer bloating, constipation, excess gas, and other gut issues, you are likely well aware that your gut is where digestion occurs…

And you want to focus on your gut health to help these issues and enjoy optimal digestion.

However, it’s important that you know your gut health is also directly tied to…

Your Vibrant Longevity

Your goal is not just to live long, but to live well while living long. And the health of your gut – including healthy levels of postbiotics – is truly mission-critical to this vibrant longevity.

For example, perhaps the most powerful postbiotic of all is called “butyrate.” And in centenarians – those who live to age 100+ ­– we see higher levels of the powerful postbiotic called “butyrate” and butyrate-producing bacteria.

Now, while the bad news is that butyrate levels in the body decline with age, the great news, as you’ll see below, is that you can take action against this decline.

Of course, we’re all the sum of our parts, so with your vibrant longevity in mind, it’s important to know that your gut health is specifically closely tied to…

Your Brain Health

That’s right, a clear and sharp brain now and very late into life is dependent, at least in part, on the health of your gut.

You see, in what researchers call the “gut-brain axis,” there’s a constant two-way communication between your gut and brain. The gut even has its own nervous system containing around 100 million neurons.

And if your gut health is “out of whack,” well, the communication and the “directions” it sends your brain can be out of whack, too… and you can easily imagine the issues that can result in your brain. Along these lines, a growing body of scientific evidence suggests that poor gut health may be directly linked to cognitive aging.

However, that’s just the tip of the iceberg, because there’s also a gut-heart axis… a gut-skin axis… a gut-muscle axis… a gut-liver axis and more.

In other words, your gut health is also directly tied to:

  • Your Heart Health
  • Your Skin Health (including looking young and healthy late into life… or not)
  • Your Muscle Health (including maintaining muscle mass as you age… or not)
  • Your Liver, Lungs & Pancreas Health and more

And as if that wasn’t enough reason to make your gut health your Priority #1, it is also ground zero for…

Your Immune System

You’ve likely heard that 70 to 80% of your immune system is based in your gut. And, indeed, this refers to what’s called the gut-associated lymphatic tissue, which comprises about 70 to 80% of your immune system and is found in your gut.

Furthermore, your gut lining is like a security fence designed to keep “foreign invaders” out. If that physical barrier is compromised – as is the case with intestinal permeability – it can lead to a host of problems throughout the body, including joint problems… brain fog… food sensitivities… fatigue… skin issues… respiratory issues… and more.

So, the bottom line on why gut health is so important?

Well, as the “Father of Medicine,” Hippocrates, seemed to know 2000 years ago when he noted that “All health issues begin in the gut”…

Your gut health really does equal your overall health and your vibrant longevity!

Prebiotics, Probiotics & Postbiotics Clearly Explained

You now know why you must make your gut health Priority #1 if you want to live long and live well.

And when it comes to achieving optimal gut health, there are basically three key pieces to the puzzle:

Probiotics, prebiotics, and postbiotics.

You’ve likely heard of probiotics, which are mainly friendly gut bacteria that support a healthy balance among the microbiota.

You may have heard of prebiotics, which in the simplest sense is “food” for the probiotics. (More specifically, prebiotics are indigestible substrates such as fibers and phytochemicals that serve as an energy source for gut bacteria.)

However, many people are not so familiar with postbiotics – which are the final and often-missing piece of the gut health puzzle!

Now, in the simplest sense, postbiotics are metabolic by-products created when probiotics feed on prebiotics.

However, don’t let the word “by-product” mislead you!

Because postbiotics are one of the – if not THE – primary means by which probiotics help our bodies stay healthy.

In other words, postbiotics are the “end game” of prebiotics and probiotics, and quite frequently, they literally represent the “missing piece” of the gut health puzzle for many people.

Now, there’s a variety of postbiotics, and the most well-known and well-researched are short-chain fatty acids (SFCAs) and – more specifically – an SFCA called “butyrate.”

And research shows this postbiotic called butyrate is very important for fueling the cells that line the gut called “colonocytes”. In simple terms, butyrate nourishes and helps seal the gut lining. Put another way, the all-important butyrate helps ensure that the “security fence” of our gut lining is well maintained and keeps the foreign invaders out.

Furthermore, butyrate is a major energy source for both the immune cells and the beneficial bacteria in the body, which are, of course, both essential to live long and well.

And, as you’ll recall above, we see higher levels of butyrate in centenarians, and this is also because butyrate may be one of the most important “players” of all in managing a healthy inflammatory response in the body as we age.

(In other words, butyrate is key for helping maintain normal levels of inflammation and for helping keep age-related inflammation – also known as “inflammaging” – in check!)

In summary, research shows butyrate is important for supporting:

  • A healthy gut lining
  • Proper immune system function
  • A healthy inflammatory response in the digestive tract (and beyond)
  • Balance and diversity in the gut microbiota
  • The body’s natural anti-aging pathways
  • Metabolic wellness (e.g., insulin sensitivity)
  • Brain health and cognitive function
  • Proper appetite signaling and regulation
  • Helping maintain muscle mass as we age


You now understand how postbiotics are the “missing third piece” of the gut health puzzle.

However, it’s important to also know WHY the piece is missing in the first place… why, in short, it has become mission-critical to supplement with a top-quality postbiotic.

And that means it’s time to round up the “usual suspects.”

Now, you’ve likely heard that the following are very bad for your health in general:

  • The inevitable toxin overload our bodies are faced with daily from foods, water, cosmetics and personal care products, the air we breathe, cleaners we use in our homes, and more…
  • The standard American diet that is far too high in processed foods, sugar, unhealthy fats, and more and far too low in produce, fiber, and more…
  • The extreme chronic stress so many people are challenged with today, including elevated levels of loneliness, anger, and other states that lead to that stress…
  • The widespread use of prescription and OTC drugs
  • The “couch disease” epidemic – i.e., most people are not getting nearly enough movement and exercise in their daily lives

And it’s key to know that these and other modern-day factors are ESPECIALLY bad for your gut health, which as you now know is key to so many aspects of your health (your brain health, immune health, heart health, and so forth).

Down to a more specific level, these modern-day factors can have a particularly bad impact on the richness and diversity of your gut microbiome, and more specific still, it can lead to a reduction in the production of postbiotics in your body, such as the all-important butyrate.

However, instead of discussing this in theory, let’s focus this on YOU in particular by having you take this simple “YES” or “NO” self-test toward understanding if you need a postbiotic.

  • Do you eat a lot of fiber from a range of different plants every day?
  • Do you eat a range of different-colored fruits and veggies on a routine basis?
  • Do you routinely eat fermented foods, such as kimchi and traditionally prepared sauerkraut?
  • Do you get ample exercise routinely and have you been doing so for quite some time?
  • Is your diet low in processed foods, sugar-added foods, and unhealthy fats and oils?
  • Do you use mostly “clean” cosmetics, personal care products, and home cleaning products that are low in potential toxins?
  • Do you routinely use air and water purifiers in your home?
  • Do you feel you have routinely low stress levels?
  • Do you refrain from smoking?
  • Do you refrain from drinking alcohol?

In brief, the more NO answers you had to the question above, the more important it is for you to consider a top-quality postbiotic supplement that provides you butyrate.

Why’s that?

Because optimal levels of postbiotics – which, remember, are the “end game” of probiotics – are dependent on having a healthy balance of those probiotics in your body.

And a healthy balance of probiotics in your body is dependent on, as you can guess, eating copious amounts of dietary fiber… a variety of colorful fruits and veggies… a routine intake of fermented foods… and getting regular exercise, which can increase butyrate production.

Furthermore, and you can guess this, too, a healthy balance of “good” gut bacteria (probiotics) is also dependent on avoiding the bad habits that can “pollute” it – such as a diet high in processed foods, smoking, and alcohol consumption, as well as exposure to environmental toxicants in the air and personal care products, and even certain medications.

Unfortunately, most people are missing the mark in at least one of these areas in this day and age.

(Speaking of age, even if you’re one of the few doing everything right, it’s still an uphill battle because we see an age-related decline in butyrate production!)

And the bottom line is, all of these factors lead to a deficiency in postbiotics – including the all-important butyrate – and that’s why it’s likely a very enthusiastic YES that you should consider a top-quality postbiotic supplement.


Because supplementing with postbiotics really is mission-critical for most people today, as you’ve seen, there are already quite a few postbiotics already hitting the marketplace and surely more to come.

Please be EXTRA CAREFUL when choosing a postbiotic, because many can be mediocre in terms of benefits and some may even be downright worthless.

A) In general, the most important thing you want to avoid is postbiotic supplements that don’t provide you CLINICALLY BACKED ingredients.

You see, there are many ingredients that could be “spun” to sound good even though they have little to no actual positive impact on you. “Clinically backed,” meanwhile, means that the ingredient was actually shown via research to have that positive effect.

B) When it comes to a postbiotic, it is also important to ensure it provides you butyrate specifically, and/or helps boost butyrate levels.

You’ve already seen why butyrate is the “all-important” postbiotic – it supports a healthy inflammatory response, healthy gut lining, proper immune system function, balance and diversity in the gut and much more, and higher butyrate levels are one of the “golden keys” in those who live 100 years plus.

Therefore, it stands to reason that the postbiotic supplement you choose should contain clinically backed ingredients that provide and help boost butyrate levels!

C) It should go without saying – though we’ll say it anyway – that any supplement you choose, including your postbiotic supplement, should be demonstrated safe and effective independent of what the company who makes it says.

Toward this end, always look for a postbiotic supplement that is manufactured in a GMP-Certified facility and that undergoes 3rd party testing to ensure purity, potency, and safety.


So, in general, you want a postbiotic supplement that provides you clinically backed ingredients that really work… that specifically provides you and helps boost butyrate, the all-important postbiotic… and that is 3rd party tested to ensure purity, potency, and safety.

More specifically, it is important to know that there are two patented ingredients out there that you want to ensure you’re taking because they are, indeed, clinically backed and simply outstanding when it comes to butyrate:

#1) ButyraGen™, the powerful “dual-action” postbiotic that directly raises levels of butyrate in the body.

ButyraGen™ is a new and advanced butyrate generator that directly raises levels of butyrate by providing an important compound called “tributyrin.”

Each molecule of tributyrin releases three molecules of the SFCA butyrate in the gut, where it is rapidly absorbed.

Additionally, ButyraGen™ contains Sunfiber®, a source of prebiotic fibers, which act through traditional gut microbiota fermentation to provide additional beneficial SCFAs, such as butyrate.

ButyraGen™ is unique because its tributyrin directly generates butyrate in the gut – no prebiotics or probiotics needed.

Even more, research has shown that ButyraGen™ increases levels of butyrate regardless of the state of the microbiota.

In other words, the gut microbiota of individuals can vary wildly, and this is why some people respond beneficially to prebiotics and probiotics, some don’t respond to them at all, and still others respond adversely.

Butyrate is generated from ButyraGen™ directly, no matter the state of the gut, meaning that nearly ALL PEOPLE CAN BENEFIT FROM IT!

Don’t be fooled by postbiotic supplements and butyrate supplements that merely claim to raise levels of butyrate.

The ButyraGen™ stands out for FACTUAL REASONS, such as:

  • Research has confirmed that ButyraGen™ raises levels of butyrate in humans; other ingredients lean on generic research to imply that their ingredients work
  • ButyraGen™ leads to minimal gas production and NO bloating
  • It has two active ingredients, tributyrin and Sunfiber® (compared to just one in many other products)
  • ButyraGen™ provides human-grade tributyrin; much of the other tributyrin on the market is just animal feed grade.
  • NO bad smells. ButyraGen™ uses a proprietary vacuum distillation process to get rid of the smell; many others have an odor that ranges from disagreeable to downright YUCK.
  • ButyraGen™ is sourced from RSPO-certified (sustainable) palm oil; many others out there come from non-certified palm oil.
  • ButyraGen™ has a two-year shelf-life; some others have a shelf-life as short as 6 months.
  • ButyraGen™ is non-GMO project verified; some others do not have this certification.
  • ButyraGen™ is also a much “cleaner” option while others are combined with a significant amount of excipients/fillers

#2) MicrobiomeX®, the “butyrate booster.”

MicrobiomeX® is a first-in-class “flavobiotic” that provides citrus flavonoids.

For starters, research has shown that these flavonoids act as prebiotics, positively modulating the composition of the gut microbiota and promoting its richness and diversity.

Along those lines, supplementation with MicrobiomeX® has been shown to increase butyrate production!

And that’s not all…

As the prebiotic flavonoids in MicrobiomeX® are metabolized by the microbiota, additional metabiotics are released in the gut – and these postbiotics directly support a healthy gut lining and proper gut barrier function by providing antioxidant support.

Two clinical studies have been carried out to date with a daily dosage of 500mg of MicrobiomeX® (the same amount in Ageless Biome). In a 12-week randomized controlled trial with 50 overweight participants, supplementation with 500mg of MicrobiomeX® resulted in:

  • Significant increases in butyrate production
  • Significant improvement in the gut microbiota (as determined by a significant increase in the amount of butyrate-producing bacteria in the gut)
  • Significant reductions in fecal calprotectin, which is an important biomarker of gut inflammation

A separate randomized controlled trial in elderly subjects showed that 500mg of MicrobiomeX® daily resulted in significant increases in the secretion of antibodies (IgA) in the gut lumen, indicating better protection against colonization by “bad” microbes.

MicrobiomeX® has the unique quality of being effective two ways, directly through its active metabolites and indirectly through a shift in the gut microbiota composition.

  • The flavonoids composing MicrobiomeX® are released after MicrobiomeX® is metabolized and directly affect the gut barrier by providing antioxidant support
  • Improvement in gut barrier function is also realized by increasing SCFA/butyrate production, which is an energy source for the epithelial cells in the gut

All in all, MicrobiomeX® exerts its positive effects in the gut multiple ways by:

  • Facilitating a shift in the gut microbiota
  • Increasing production of SCFAs, such as the all-important butyrate
  • Enhancing gut barrier function and improving mucosal protection
  • Promoting a healthy inflammatory response in the digestive tract

In the end, MicrobiomeX® promotes gut health by preferentially modulating the composition of the gut microbiota, increasing levels of butyrate, promoting healthy gut barrier function and supporting a healthy inflammatory response in the gut.


It’s now clear in the health community that a postbiotic is about as essential as it gets to your gut health – and therefore, to your overall health and vibrant longevity.

Because this is true, the scientific team at BioTRUST, America's #1 online nutrition brand, worked hard to provide you what we believe is the BEST postbiotic supplement available today

Ageless Biome.

Yes, Ageless Biome provides you the effective 200mg per serving amount of the clinically-backed ButyraGen™, the powerful “dual-action” postbiotic that directly raises levels of butyrate in the body.

Yes, Ageless Biome also provides you 500mg per serving of the clinically-backed MicrobiomeX®, the “butyrate booster.”

Yes, Ageless Biome is manufactured in a GMP-certified facility and undergoes 3rd party testing to ensure purity, potency, and safety.

Plus, Ageless Biome is simple-as-can-be to consume: Just take 2 easy-to-swallow capsules, with or without food, in the morning and that’s it!

Best of All, It's From BioTRUST

BioTRUST is America's premier online nutrition brand known for having shipped over 15 million premium, honest nutrition products made with researched-backed, naturally-derived ingredients to our loyal customers around the world. BioTRUST was started in 2011 as a nutrition company that was authentic, honest, and always put quality and service first. Toward that end, BioTRUST...

  • Has independent labs test products to ensure the potency and purity of every product we develop.
  • Ensures the quality of all products is verified by a certificate of analysis.
  • Works only with top-tier manufacturers.
  • Takes enormous pride in providing customers with world-class customer service and a 5-star customer experience.
  • Cares about community, too. To date, BioTRUST has helped provide over 5.6 million meals* to hungry kids through our partnership with the nonprofit® and we've helped grant over 220 wishes for kids with life-threatening medical conditions through our partnership with Make-A-Wish®.

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With your Ageless Biome order, you are immediately getting the eReport that provides the clear and easy details on every step you’ll be taking, along with steps you can take to heal your gut.

With BioTRUST, you’re always protected by the naturally honest 60-Day Total Satisfaction Guarantee. If for any reason at all you are unsatisfied with your purchase, just send it back – even empty bottles – for a fast and friendly refund of the full purchase price up to 60 days after securing your order today.

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BioTRUST cares about our customers and community. For every Ageless Biome order today, we help support programs that feed hungry children through our partnership with®. To date, BioTRUST has helped provide over 5.6 million meals* to hungry kids.

What's more, with the support of our customers, we've funded over 220 wishes for kids with life-threatening medical conditions through our partnership with Make-A-Wish®. Through our partnership with Pencils of Promise®, BioTRUST has helped build three schools for underprivileged children, and along with®, we've provided clean drinking water for hundreds of families in third-world countries. It's support from customers like you that allows us to give back. Thank you!

*No Kid Hungry® does not provide individual meals; donations help support programs that feed children. Learn more at

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You now know these 6 facts:

  1. Your gut health is mission-critical to your overall health and your vibrant longevity.
  2. Postbiotics are the “missing 3rd piece” to optimal gut health.
  3. The all-important postbiotic, butyrate, naturally declines with age PLUS so many modern-day lifestyle habits contribute further to its decline.
  4. You want to be very careful of any postbiotic supplement that doesn’t contain clinically-backed ingredients… and of any supplement that does not undergo 3rd party testing to ensure purity, potency, and safety.
  5. The two clinically-backed ingredients, ButyraGen™and MicrobiomeX®, provide butyrate and are shown to boost butyrate levels.
  6. Ageless Biome uniquely provides you the effective amounts of BOTH ButyraGen™ and Microbiome®, and it is 3rd party tested to ensure purity, potency, and safety.

Yes, as you can tell, this particular supplement is as important as supplements get, and right now is the ideal time to experience the difference it will make for you.

That’s because right here, on this page only below, you’re getting a full-sized bottle of Ageless Biome at its lowest price anywhere, up to 36% OFF – plus you’re getting 3 bonuses including FREE U.S. shipping!

How Much Should I Order?

  • Each bottle of Ageless Biome provides you 60 capsules, and because you’ll take 2 capsules each morning, that’s a one-month supply. Of course, the goal is to keep your butyrate levels high, so you won’t want to run out, making the better savings with the 3 or 6 bottle options below your smartest choice.
  • Half of all customers order an extra bottle or two for their family, friends, or significant other – another reason to consider multiple bottles.
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  • These are the guaranteed lowest prices you'll find anywhere on Ageless Biome.
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Q: What specifically makes Ageless Biome the right choice for you?

A postbiotic supplement is the “missing third piece” of the gut health puzzle, key to supporting your digestive health, brain health, heart health, skin health, immune health and more. And Ageless Biome stands heads and shoulders above others because it provides you the clinically backed ButyraGen and the clinically backed MicrobiomeX®. Research confirms that ButyraGen™ raises levels of the powerful postbiotic, butyrate. Plus, ButyraGen™ provides Sunfiber®, a prebiotic fiber that can lead to even greater production of postbiotics. Meanwhile, research also confirms that MicrobiomeX® increases production of the powerful postbiotic, butyrate, and it’s a first-in-class “flavobiotic,” a unique category of prebiotics shown to promote richness and diversity in the gut’s microbiome. Finally, unlike certain other probiotics out there, Ageless Biome is manufactured in a GMP-certified facility and undergoes 3rd party testing. This ensures potency, purity, and safety!

Q: What are the ingredients and amounts used in the formula?

Q: What is the best way to use Ageless Biome?

Take two capsules, with or without food, in the morning.

Q: How many servings are in a bottle of Ageless Biome?

Each bottle of Ageless Biome contains 30 servings.

Q: Does this product contain caffeine or any other stimulants?

No. This product is caffeine- and stimulant-free.

Q: Are there any allergy concerns with this product?

Ageless Biome is manufactured in a facility that also processes egg, fish, soy, crustacean shellfish, tree nuts and wheat. Always review the label for the most accurate information.

Q: What if this product doesn’t work for me?

While Ageless Biome was created to work, if for any reason at all you are unsatisfied with your purchase, just send it back to us, and we will issue a prompt and courteous refund even on empty bottles. You’re always protected by our naturally honest 60-Day Money Back Guarantee.

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