What Happens to Joints as We Age?

Are your joints holding you back from doing the things that matter most to you?

• Working around the house or gardening?
• Being as active as you’d like to be?
• Participating in sports activities as often or at the level you’d prefer?

If so, you’re not alone. In fact, research shows over 40% of folks over the age of 40 are concerned or complaint about their joints, and even more, it’s estimated that 80% or more of people who are 65 or older have some degree of joint wear and tear.

But even if it’s “normal,” it’s not “right.” After all, if your joints aren’t limber and healthy, that can limit your mobility, activity level, and independence and negatively impact your quality of life. Simply put, if your joints aren’t in tip-top shape, that can keep you from doing what you love to do and living the life of your dreams.

According to researchers, there are two big elephants in the room when it comes to declining joint health: 1. Age; and 2. Being overweight.

In the case of the latter, body weight has a direct impact on the amount of pressure placed on joints. For instance, it’s estimated that a force of 3 – 6 times one’s body weight is exerted across the knee when walking. In other words, being just 10 pounds overweight can mean your knees have to bear the burden of up to 60 additional pounds of force with each step.

What’s really interesting though is that being overweight is linked to joint issues in non-weight bearing joints as well, such as the hands. This goes to show that there may be something else to the story, and it’s thought that excess body fat releases compounds that contribute to declining joint health.

Certainly, a poor diet plays a role, and of course, lots of physical activity (particularly repetitive types of movements) can take a serious toll on joint health.

But what happens to joints as we age? Can a joint supplement help?

Well, as we get older, there are three common structural factors that contribute to declining joint health and function:

1. Poor collagen health, production, and formation

Collagen is the primary structural protein in cartilage—the spongy connective tissue that cushions the ends of your bones where your joints meet. Essentially, cartilage protects your bones from grinding against each other, bone on bone, which would be extremely painful. As you age, however, less cushioning is available (particularly less type II joint collagen), leading to fragile-feeling joints and reduced joint health and function.^†

2. Inadequate levels of lubricating joint fluid

Hyaluronic acid is the chief component of joint fluid, also known as synovial fluid, which helps reduce the friction between bones by providing lubrication between cartilage. As cartilage deteriorates with age so do levels of hyaluronic acid and synovial fluid production, making it excessively difficult for joints to move freely—kind of like the hinges on a squeaky door.^†

3. Increased collagen breakdown

Healthy levels of joint- and collagen-degrading enzymes, known as 5-LOX and MMPs, are important for normal, ongoing rebuilding of joint tissues. However, 5-LOX and MMPs can run rampant in worrisome joints, leading to even greater collagen breakdown.^†

In plain English, this means that all people can experience suboptimal joint health when their joints aren’t getting the proper support they need—like the nutrients that form building blocks needed to support healthy levels of cartilage and proper lubrication in the joint.

The Problem with Most Joint Health Supplements

Unfortunately, the typical joint supplement misses the mark, usually only addressing one of the joint health problems mentioned above. Even then, popular joint supplement ingredients are often marginally effective at best.

Take, for example, the most common joint supplement ingredients: glucosamine and chondroitin. In one of the largest randomized controlled trials (GAIT) published in the prestigious New England Journal of Medicine, researchers randomly assigned 1,583 study participants to receive either glucosamine, chondroitin, both, an alternative intervention, or placebo for 24 weeks.^†

At the end of the 6-month study, the folks supplementing with glucosamine and chondroitin did NOT experience any greater improvements in joint function than the placebo group. In other words, the two popular joint supplement ingredients glucosamine and chondroitin alone or in combination were not effective at improving joint health.

Another big problem with other joint health supplements is that they often require taking 6 – 8 (or more) very LARGE capsules per day—often multiple times. Unfortunately, these are big hurdles to jump over as studies show that increased capsule size, capsule number, and frequency of taking capsules all negatively impact compliance, and if you can’t pop the right number of pills regularly, you can’t expect to reap the expected benefits of your joint supplement.

What Makes Joint 33X the Best Joint Supplement?

Thankfully, all hope is not lost. Just because most other joint health supplements miss the mark doesn’t mean we did too.

In fact, we developed a joint supplement to address the three main contributors to suboptimal joint health and function, and we call it Joint 33X, a next generation joint supplement that features three patented, joint-nourishing ingredients that have been demonstrated to support joint health, mobility, flexibility, and function in more than a dozen human studies.^†

1. Build and restore with UC-II^®

For starters, Joint 33X joint supplement features UC-II, which provides a unique, highly effective form of undenatured type II collagen. Remember, collagen is the primary structural protein in connective tissues in the human body, including bones, cartilage, skin, and tendons, and it’s the wearing down of type II joint collagen that is associated with reduced joint health and function.

Four separate studies have tested the mettle of UC-II, which has been shown to support joint health and mobility by promoting healthy levels of collagen. Even more, UC-II has been shown to be significantly more effective at improving joint flexibility and function than the popular joint supplement ingredients glucosamine and chondroitin in head-to-head research.^†

2. Lubricate joints with Hyal-Joint^®

The next all-star ingredient in Joint 33X joint supplement is Hyal-Joint^®, a natural extract that is rich in hyaluronic acid. Remember, joint wear and tear is typically characterized by reduced quantity and quality of hyaluronic acid, and along those lines, Hyal-Joint^® helps lubricate and cushion joints.^†

Hyal-Joint^® also contains collagen, the main protein present in joints and the key to flexible, strong tissue, as well as other glycosaminoglycans, which also play an important role in joint performance. In fact, Hyal-Joint^® also supports joint function and muscle strength. The joint health benefits of Hyal-Joint^® have been demonstrated in a half-dozen human studies.^†

3. Protect with AprèsFlex^®

Finally, Joint 33x joint supplement features AprèsFlex^® Boswellia extract, which targets mediators (such as 5-LOX and MMPs) of comfort and flexibility. By supporting normal, healthy levels of these compounds, AprèsFlex^® supports healthy joints and connective tissues.^†

Two separate human studies have confirmed the potential of this next-generation Boswellia extract. Even more, research shows that study participants experience results they can feel in much less time than is typical with more popular joint supplement ingredients, such as glucosamine and chondroitin.^†

What's more, Joint 33X joint supplement promotes results you can feel in less time than you might think with just ONE small capsule you take ONCE per day.

Simply put, we truly believe Joint 33X sets the bar as the best joint supplement, and we’re confident that you’ll agree!

Joint 33X Nutrition & Ingredients

Joint 33X is a next generation joint supplement featuring three patented, joint-nourishing ingredients that have been shown to support joint health, mobility, flexibility, and function in more than a dozen human studies.^† Unlike most joint supplements, Joint 33X promotes results you can feel in less time than you might think with just ONE small capsule you take ONCE per day. Here are three key ingredients in Joint 33X:

• UC-II^® supplies undenatured type II collagen, which supports joint health and mobility by promoting healthy levels of collagen. UC-II has been shown to be significantly more effective at improving joint flexibility and function than the popular joint supplement ingredients glucosamine and chondroitin in head-to-head research.^†
• Hyal-Joint^® is a natural extract that is rich in hyaluronic acid, collagen, and glycosaminoglycans, which support joint mobility and function. Hyal-Joint^® helps lubricate and cushion joints.^†
• AprèsFlex^® Boswellia extract supports healthy joints and connective tissues by targeting mediators of comfort and flexibility and supporting normal, healthy levels of these compounds.^†